We have 4 tools:

MPRA (Motifs) construction

Allows the substitution of motifs in a background sequence at all possible positions within the constraints of the parameters

MPRA (SNPs) construction

Allows the substitution of reference positions with SNPs

Transmutation

Creates a specified number of random mutations on a sequence

PWM-SeqGen

Generates simulated sequences using PWMs.

Download Scripts

Click here for a Python script that converts original coordinates to equal sized, centered coordinates with range X nucleotides on each side.

API scripts

Click here for a Python script for programmatically querying MPRA motifs.

Click here for a Python script for programmatically querying MPRA SNPs.